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硕士生导师

主要学习工作经历

2015-至今,中国中医科学院中药资源中心工作

2009-2015年,中国科学院遗传与发育生物学研究所 硕博

2005-2009年,东北林业大学 本科

主要社会兼职

iMeta 杂志执行主编

主要研究内容

围绕数据驱动的中药道地性形成和高品质生产研究开展:⑴ 中药大数据资源底座的持续建设;⑵ 中药大数据模型开发和中药资源的智算整合挖掘。以及基于数据库联合开展①中药道地性形成分子机制研究;②高品质中药生产和鉴定;③中药合成生物学研究和中药新资源挖掘。

开发有大数据在线绘图和分析平台ImageGPBICEVenn、植物整合基因组平台IMP获中华中医药学会 2023 年年度十大学术进展之一),使用数百万人次。

主要研究成果

一、代表性论文及论著:

(一)代表性论文(*通讯作者):

1. Chen,T*, Liu,Y.-X.*, Chen,T., Yang,M., Fan,S., Shi,M., Wei,B., Lv,H., Cao,W., Wang,C., Cui,J., Zhao,J., Han,Y., Xi,J., Zheng,Z., and Huang,L.*. (2024). ImageGP 2 for enhanced data visualization and reproducible analysis in biomedical research. iMeta 3,5, e239

2. Chen,T.†, Yang, M.†, Cui, G., Tang, J., Shen, Y., Liu, J., Yuan, Y.*, Guo, J.* and Huang, L.*. (2024) IMP: Bridging the Gap for Medicinal Plant Genomics. Nucleic Acids Res, 52(D1):D1347-D1354 

3. Huang,L., Wang,D., Chen,H., Hu,J., Dai,X., Liu,C., Li,A., Shen,X., Qi,C., Sun,H., Zhang,D., Chen,T.*, Jiang,Y.*.(2023) CRISPR-detector: fast and accurate detection, visualization, and annotation of genome-wide mutations induced by genome editing events. Journal of Genetics and Genomics 50:563-572. 并列通讯 

4. Lei,B., Xu,Y., Lei,Y., Li,C., Zhou,P., Wang,L., Yang,Q., Li,X., Li,F., Liu,C., Cui C, Chen T*, Ni W*, Hu SW*. (2023) CRAMdb: a comprehensive database for composition and roles of microbiome in animals. Nucleic Acids Res, 51, D700–D707. 并列通讯

5. Chen,T., Liu,Y.-X. and Huang,L. ImageGP: An easy-to-use data visualization web server for scientific researchers. iMeta, 2022, 1(1):e5.

6. Chen T., Zhang H., Liu Y., Liu Y.-X.*, and Huang, L.*. (2021). EVenn: Easy to create repeatable and editable Venn diagrams and Venn networks online. Journal of Genetics and Genomics 48(9):863-866

7. Liu Y.-X.†*, Qin Y. †, Chen, T. †, Lu, M., Qian, X., Guo, X., and Bai, Y.*. (2021). A practical guide to amplicon and metagenomic analysis of microbiome data. Protein Cell 12, 315–330. 并列一作

8. Ma, Y. †, Cui, G. †*, Chen, T. †, Ma, X., Wang, R., Jin, B., Yang, J., Kang, L., Tang, J., Lai, C., et al. (2021). Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza. Nat Commun 12, 685. 并列一作

9. Gao J.†, Chen T.*, Jiang, C. et al. (2021). Comparative anatomical and transcriptomic analyses of the color variation of leaves in Aquilaria sinensis. PeerJ 9, e11586. 并列通讯

10. Liu, J.†, Chen, T.†, Zhang, J .†, Li, C., Xu, Y., Zheng, H., Zhou, J., Zha, L., Jiang, C., Jin, Y., et al. (2020). Ginsenosides regulate adventitious root formation in Panax ginseng via a CLE45-WOX11 regulatory module. J Exp Bot 71, 6396–6407. 并列一作

11. Tong Chen, Ya-Juan Hao, Ying Zhang, Miao-Miao Li, Meng Wang, Weifang Han, Wu,Y., Lv,Y., Hao,J., Wang,L., et al. (2015) m6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency. Cell Stem Cell, 16, 289–301. 封面文章